Of note, Tian et al. (2019) have provided detailed data confirming the function and presenting a mode of action for LINC00320 in glioma progression whereby LINC00320 exerts inhibitory effects on glioma cell proliferation by restraining the Wnt/β-catenin signaling through segregating β-catenin and transcription factor 4 (TCF4). Here, TCF4 is linked to central nervous system cancer.