PGR and ductal breast carcinoma in situ: Analysis of the 12-year follow-up data of the Eastern Cooperative Oncology Group (ECOG) E 5194 trial has confirmed the role of histological features (high grade) in predicting likelihood of recurrence.15 This was also confirmed in analysis of 57,222 DCIS cases from the SEER database by Sagara et al.16 The expression of oestrogen and progesterone receptors (ER and PR) is also associated with decreased risk of recurrence.