AGO1 and nonpapillary renal cell carcinoma: We found that high miR-153-5p + low AGO1 group had the worst prognosis (vs. low miR-153-5p + high AGO1 group: P < 0.001, HR = 3.51; vs. high miR-153-5p + high AGO1 group: P < 0.001, HR = 2.67; vs. low miR-153-5p + low AGO1 group: P = 0.04, HR = 1.48), indicating miR-153-5p/AGO1 axis serves as a robust prognostic indicator in ccRCC.