ITGA2B and COVID-19: In addition, we detected a higher spontaneous expression of some constitutive receptors and adhesion molecules involved in platelet activation and aggregation in COVID-19 platelets, such as the transmembrane integrins GPIIb (p = 0.0001) and GPIIIa (p < 0.0001), as well as the glycoproteins GPIbα (p = 0.0086) and GPIX (p = 0.0126, Fig. 2b).