PIDD1 and autism spectrum disorder: Recent whole-genome sequencing efforts for autism spectrum disorder proband/mother/father trio through the Autism Speaks/MSSNG study also has some evidence for PIDD1 as a rare risk gene—out of ~10,000 trios sequenced, a single affected individual (AU2798301) is reported to show compound heterozygous variants: maternal allele: chr11:802296G>C; NM_145887:exon6:c.C1075G; p.(Arg359Gly); paternal allele: chr11:802684G>A, NM_145887:exon4:c.C917T:p.Pro306Leu.