TNFAIP3 and nasopharyngeal carcinoma: In NPC, EBV is integrated into introns of the inflammation-related genes PARK2, tumor necrosis factor alpha-induced protein 3 (TNFAIP3), and cyclin-dependent kinase 15 (CDK15), which regulate the nuclear factor-κB pathway.13 However, this behavior was not observed in pLELC.