The results indicated that SCEL was overexpressed in GBC tumor tissues (P = 0.0211; Fig. 1C).To validate this elevated level in GBC and clinical relevance of SCEL with the development of GBC, we extended our study to enroll 49 human GBC specimens and analyzed expression levels and relationship of SCEL with clinical outcomes (Fig. 1E, Table 1). Here, SCEL is linked to neoplasm.