Then, UCP1 that is exclusively expressed in beige/brown adipocytes, PRDM16 that is a master regulator of brown adipocyte differentiation, gene expression for classical brown (MYF5, EVA1, and OPLAH) as well as beige (CD137/TNFRSF9 and TBX1) adipocyte markers is enriched in the samples of human and mouse breast cancer. This evidence concerns the gene TNFRSF9 and breast carcinoma.