Similarly, enzymes involved in auxiliary pathways including peroxisomal 2,4-dienoyl CoA reductase (DECR2), which is related to mitochondrial DECR1, peroxisomal Δ3, Δ2-enoyl-CoA isomerases, and downstream export processes catalyzed by peroxisomal carnitine octanoyltransferase (COT), carnitine acetyltransferase (CAT), and ACOTs (see reviews [305, 308]) are currently not well described in cancer. Here, DECR1 is linked to cancer.