MBOAT7 and neoplasm: Other members of the LPLAT family have also been implicated in tumor biology, including increased LPCAT2 supporting chemoresistance in colorectal cancer [267, 268], increased protein levels in breast and cervical cancer tissue [269], loss of LPCAT3 enhancing intestinal tumor formation via a cholesterol synthesis mechanism [270], and lysophosphatidylinositol-acyltransferase 1 (LPIAT1) mediated prostaglandin production and non-small cell lung cancer cell growth [271].