PDGFRB and anaplastic large cell lymphoma: In the CD4-NPM-ALK mouse model, c-Jun and JunB were found to promote transcription of the Platelet-Derived Growth Factor Receptor β (PDGFRβ), a receptor tyrosine kinase, which was subsequently found to be highly expressed in ALK+ ALCL patient samples and some ALK+ ALCL cell lines [93].