The dual staining apoptosis assay and TUNEL assay results showed that the number of apoptotic tumor cells was the highest in the group treated with the combination of GRP78 knockdown and irradiation (Figure S1F, G), coinciding with the western blotting results for the apoptosis-related protein cleaved PARP (c-PARP) and the radiation injury marker γ-H2AX (Figure S1H). The gene discussed is H2AX; the disease is neoplasm.