Gene fusions of NRG1 such as CD74-NRG1 and SLC33A2-NRG1 have been found at low frequency in a wide range of carcinomas including lung, breast, colorectal, ovarian, and pancreatic cancers and with a wide range of fusion partners ([4–9], reviewed in [10]). This evidence concerns the gene NRG1 and familial pancreatic carcinoma.