Moreover, PA inhibited the expression of aortic-associated macrophage inflammatory cytokines, such as IL-1β, iNOS, MCP-1, IL-6, and chemokine (C-X-C motif) ligand 11 in mouse model systems; these results demonstrated that PA could promote the attenuation of atherosclerosis, possibly by inhibiting macrophage infiltration and its inflammatory responses [16]. Here, NOS2 is linked to atherosclerosis.