In addition, MDP treatment still moderately increased the tumor burden in lamin A/C△hep mice (tumor number: 16.50 ± 2.43 vs. 22.75 ± 3.92, P < 0.01; tumor size: 6.58 ± 1.53 vs. 9.38 ± 1.51, P < 0.01) (Fig. 7b). The gene discussed is LMNA; the disease is neoplasm.