MKI67 and neoplasm: In Cox proportional hazards model for multivariate survival analysis, pre-NACT ADAM10 (HR = 3.67, p = 0.028), Ki67 index (HR = 3.33, p = 0.049), tumor size (HR = 2.84, p = 0.045) and lymphatic metastasis (HR = 8.13, p = 0.002) had a statistically significant effect on overall survival.