After adjustment for age, gender, change in CD4 count from baseline to week 4, and time from TB treatment to ART initiation, baseline restriction and mixed pattern remained significantly associated with impaired pulmonary function at 12 months (aOR for baseline restriction 5.44, 95% CI 1.16–25.45; aOR for baseline mixed 9.00, 95% CI 1.05–76.87). This evidence concerns the gene CD4 and tuberculosis.