In 2005, other diagnostic tests for differentiating CD from ectopic ACTH producing tumor such as inferior petrosal sinus sampling (IPSS), corticotropin releasing hormone (CRH) stimulation test, octreotide scan or fluorodeoxyglucose (FDG)-positron emission tomography (PET) scan were not available in our country. The gene discussed is CRH; the disease is neoplasm.