Therefore, the 2019 ESC Guidelines for the Management of Dyslipidemias recommended that: for patients who present with an ACS and whose LDL-C levels are not at goal, despite already taking a maximally tolerated statin dose and ezetimibe, the addition of a PCSK9 inhibitor early after the event (during hospitalization for the ACS event if possible) should be considered, in order to obtain earlier cardiovascular benefits [34]. This evidence concerns the gene PCSK9 and metabolic syndrome.