Apolipoprotein B was an innate barrier against bacterial infection,41 and novel APOB mutations were observed in autism.42 The Bacteroides eggerthii was reported to enhance colitis in mice.43 Studies have reported that the Bacteroidetes/Bacteroidales were among the key taxa related to vitamin A in ASD children.44 Other associations include the thiamine transporters SLC19A3 (rs117864472, c.A1132G, p.I378V) and Clostridiales bacterium VE202-03, among others. Here, APOB is linked to colitis.