Comparing the CF mice with and without supplementation (Table 5 and 6), we observed that all the parameters resulted not significantly different, except for serum phytosterols levels, that were significantly lower in the supplemented CF mice (2.0 fold), and the liver cholesterol and TNFα mRNA levels that were significantly higher in the supplemented CF mice (1.3 fold and 5.0 fold, respectively; Fig 1). This evidence concerns the gene TNF and cystic fibrosis.