CEL and cystic fibrosis-related liver disease: This finding suggests that the supplementation of pancreatic enzymes is not sufficient to allow a normal lipid digestion in CF patients with PI [8] probably due to the small amount of cholesterol esterase in supplementation therapy [9] as well as to the reduced synthesis, secretion [10] and reabsorption of bile salts [11] caused by different degrees of CF liver disease (CFLD) [12, 13].