IGFBP7 and acute kidney injury: Combination of po-AKI stages 2 and 3 (as analyzed previously [13,19]) did not change the discriminatory power of the analysis (no statistical significant differences in (TIMP-2) x (IGFBP7) values of patients with (AKI stages 2+3)/ without (AKI stages 0+1) AKI on POD1 (median 0.39 vs 0.26, p = .05) (S3 Fig).