While Wt animals showed a significant increase of aldolase expression 3 and 6 days after TAC, the expression in Cx3cr1GFP/GFP mice did not change, corroborating the finding that cardiac hypertrophy is attenuated in the absence of CX3CR1 signaling (Fig 2B). The gene discussed is CX3CR1; the disease is cardiac hypertrophy.