ACE and hypertensive disorder: The LASSO multivariate analysis found age, number of comorbidities, extension of ground glass opacities on chest CT and troponin with a direct relationship with all-cause mortality, whereas dysgeusia, use of angiotensin converting enzyme inhibitor or angiotensin-ii receptor blocker and number of lymphocytes with an inverse relationship with all-cause mortality In different studies older age, hypertension, diabetes melitus, dyspnea, number of comorbidities, and laboratory parameters were associated to increased risk of mortality in patients with COVID-19 [28, 29].