We analyzed these abnormal genes and HOXB9 mRNA expression in NSCLC and normal lung tissues from GEO public databases (GSE74706) and found that the expression levels of HOXB9, EGFR, KRAS and BRAF were significantly increased in NSCLC (Supplementary Figure 2A). The gene discussed is EGFR; the disease is non-small cell lung carcinoma.