All 11 RBPs (BRIX1, DYNC1H1, GTPBP4, PRKDC, RAN, RBM19, SF3B4, SMG5, SPATS2, TAF9, and THOC5) were found to be significantly higher in patients with advanced tumor grade (p < 0.05). The gene discussed is BRIX1; the disease is neoplasm.