Indeed, in support of this scenario it has been reported that many NB exhibits high ALK expression in the absence of mutation and that these high levels correlate with poor progression (Lamant et al, 2000; Osajima‐Hakomori et al, 2005; Janoueix‐Lerosey et al, 2008; Mosse et al, 2008; Passoni et al, 2009; Duijkers et al, 2012; Wang et al, 2013; Regairaz et al, 2016; Javanmardi et al, 2019). Here, ALK is linked to neuroblastoma.