We also noted increased levels of VGF both in Alk‐F1178S;Th‐MYCN and Rosa26_Alkal2;Th‐MYCN tumours (Fig 5F and G), in agreement with our earlier observation of strongly upregulated VGF protein levels in NB1 cells stimulated with ALKAL2 (Fig 2, Table EV2) and a previous report of increased Vgf mRNA levels in an ALK gain‐of‐function NB mouse model (Cazes et al, 2014). The gene discussed is ALKAL2; the disease is neoplasm.