The hematological parameters show that the values of the hemoglobin (Hb), RBCs, WBCs, platelets, and prothrombin concentration were significantly decreased in HCC than in control groups (P < 0.001), while the creatinine and total bilirubin levels were not different significantly among the two groups (P > 0.05). This evidence concerns the gene GSTM1 and hepatocellular carcinoma.