Although RBD symptoms can be seen in several disorders, such as narcolepsy-cataplexy and parasomnia overlap disorder, and may be precipitated by certain drugs, such as selective serotonin reuptake inhibitors [1], its isolated presence in the general adult population is closely linked with alpha synuclein neuropathology and a future diagnosis of either Parkinson’s Disease (PD), Dementia with Lewy Bodies (DLB) or Multiple System Atrophy (MSA) [2, 3]. This evidence concerns the gene SNCA and multiple system atrophy.