NF2 and breast cancer: In order to investigate the functional and mechanistic role of Merlin on mammary tumor development in vivo, we generated a Nf2fl/fl MMTV Neu mouse model and intraductally injected female mice with Cre‐expressing lentivirus to generate a mammary‐specific Nf2 knockout mouse (Nf2−/− MMTV Neu+) (Fig. 5A).