An additional source of myofibroblasts comes from the EMT process (Zeisberg M. et al., 2007; Zhao et al., 2016) whose involvement in liver fibrosis has been demonstrated in several studies (Inagaki et al., 2003; Seki et al., 2007; Feng et al., 2013; Li et al., 2017; Park et al., 2017) due to the activation of pro-EMT pathways, such as the TGF-β. This evidence concerns the gene TGFB1 and Hepatic fibrosis.