TGFB1 and Hepatic fibrosis: Baicalin therapy can be effective in alleviating liver fibrosis in rat models, with a reduction of hepatic hydroxyproline, alanine and aspartate aminotransferases, ALT and AST (the most commonly used liver injury markers), the reduction of TGF-β1, TNF-α and IL-6 levels and the abrogation of deposition and accumulation of collagen (Peng et al., 2009).