In diffuse large B cell lymphoma (DLBCL), metabolic diversity is related to different expression profiles identified as a three-consensus cluster today used for DLBCL classification: B cell receptor (BCR)/proliferation cluster (BRC-DLBCL), oxidative phosphorylation cluster (OX-PHOS DLBCL), and host response (HR) cluster (102). Here, BCR is linked to diffuse large B-cell lymphoma.