In yet another study evaluating the relationship between major depression and the glucose control index among type II diabetics, from 134 patients, using HAM-D, a significantly higher depressive score was reported among patients with diabetes having hypertension (p=0.001), asthma (p-0.01), and on insulin treatment (p=0.005) [25]. The gene discussed is INS; the disease is type 2 diabetes mellitus.