However, we did not detect any significant difference between the visfatin level before and after SRP in unstimulated salivary samples of diabetic patients (P=0.221) Raghavendra et al29 reported higher concentrations of serum and GCF visfatin in patients with periodontitis than those with healthy periodontium, and visfatin concentration decreased after SRP treatment and reached the level similar to that of the healthy subjects. The gene discussed is NAMPT; the disease is periodontitis.