Progranulin, which is also recognized as acrogranin, granulin or proepithelin, is an adipokine released from epithelial cells, neurons, immune system cells, and chondrocytes.32 It is released from ameloblasts, odontoblasts, and osteoblasts and plays a crucial role in the early stages of embryogenesis, odontogenesis, and amelogenesis.33 Progranulin has been linked with abdominal obesity, increased plasma glucose, and lipid disorders,34 and is involved in the wound healing, inflammation, and tissue defense.33 The gene discussed is GRN; the disease is Abdominal obesity.