LDLR and breast carcinoma: Many studies have demonstrated increased LDLR expression and LDL cholesterol uptake in a variety of tumours, such as leukemia, lung cancer, glioblastoma, breast cancer, and pancreatic cancers (Guillaumond et al., 2015; Guo et al., 2011; Kimbung et al., 2016; Vitols et al., 1990, 1992).