NCOA3 and infection: To investigate whether AIB1 has effects on PDAC progression, we chose two PDAC cell lines (PANC-1 and MIA PaCa-2) with high AIB1 abundance, and AIB1 expression was stably silenced in these cells by infection with two different lentiviral shRNAs against AIB1 (shAIB1-1 and shAIB1-2).