It is clear that in the top ten genes in PPI network of CESC, ESCC, and LUSC, nine of them (BUB1, BUB1B, CCNA2, CCNB1, CCNB2, CDC20, CDC6, CDK1, and MAD2L1) are the same. The gene discussed is CDC6; the disease is cervical squamous cell carcinoma.