We first screened the GEO database and collected three datasets of TAMs in glioma, the GSE80338 and GSE115397 collected CD11b+ microglia/macrophages from glioma and normal brain tissue and sequenced using RNA sequencing, while the GSE135437 was using FACS sorted on lineage-negative live CD45-positive cells and sequenced using the mCEL-Seq2 protocol. The gene discussed is ITGAM; the disease is central nervous system cancer.