Moreover, neurotransmission in the hippocampal Schaffer-collaterals fibers and their excitability were not affected by the chronic exposure to acoustic stimulation in Wistar rats (Cunha et al., 2015) and AuK-dependent limbic recruitment in WARs is not associated with any inflammatory process or oxidative stress, suggesting that this neuroplastic anatomical change is a “network expansion process,” primarily linked to the genetic selection for the epilepsy phenotype in WARs (de Deus et al., 2020). Here, WARS1 is linked to epilepsy.