VEGFB and neoplasm: Traditional studies on VEGF-B largely concentrated on their effects on neurotrophy, angiogenesis, and neuroprotection, while some ruled out the association between VEGF-B overexpression and tumor growth, invasion, diabetic retinopathy and others (Abedin et al., 2010[2]; Falk et al., 2009[9]; Olofsson et al., 1996[29]; Zhong et al., 2011[43]).