By searching starBase and Targetscan, we found nine miRNAs that were commonly predicted to bind to and down-regulate SPC25 expression in HCC: hsa-miR-369-3p, hsa-miR-369-3p, hsa-miR-374a-5p, hsa-miR-380-3p, hsa-miR-451a, hsa-miR-379-3p, hsa-miR-411-3p, hsa-miR-190b, hsa-miR-374b-5p, hsa-miR-1276 (Figure 6A). The gene discussed is SPC25; the disease is hepatocellular carcinoma.