Our study, which employed the tg(Grm1)EPv spontaneous melanoma mouse model, provides strong evidence that enhancing DC numbers and activation can improve the recruitment of intratumoral T cells by upregulation of chemokines required for the recruitment of T cells, including the type I IFN-inducible CXCL9 and 10 chemokines.46 As checkpoint blockade alone did not mediate these effects, the DC boost approach appears to be key in this process. Here, CXCL9 is linked to melanoma.