Pathway analysis also identified dysregulation of AD-related genes, including amyloid beta (A4) precursor protein-binding, family B, member 1 (APBB1 probe set id: 202652_at) (FC, −1.64; P = 0.026) and membrane metalloendopeptidase (neprilysin) (MME probe set id: 203434_s_at) (FC, +1.37; P = 0.049). This evidence concerns the gene MME and Alzheimer disease.