Among the 13 genes that was built of the breast cancer risk prediction model, the expression levels of ANXA5 were related to stage T (P = 0.028) and age (P = 0.004), CD3E expression levels (P = 0.017) were only related to age, GSTZ1 (P = 0.040), GZMM (P = 0.006), GRHPR (P < 0.001), UBTF (P = 0.004) and CHP1 (P = 0.003) were significantly related to stage M (Fig. 6h). The gene discussed is CHP1; the disease is breast cancer.