IL5 and asthma: Also, it was observed that the percentage of Th2 cells in peripheral Th cells, and IL-5 in sputum were significantly higher in children with eosinophilic asthma than those in children with neutrophilic and paucigranulocytic asthma, which suggested that Th2-mediated immunity played a predominant role in the pathogenesis of eosinophilic asthma.