Other case-specific, n-of-one enriched mutations included nonsense mutations in ARID1A (Q1424*, case ERLR_20, primary AF 0.5%, recurrence AF 16.5%) and BRD1 (Q467*, case ERLR_01, primary AF 0.93, recurrence AF 57.88%), an acquired TP53 mutation (S241C, case ERLR_03, primary AF 0.0%, recurrence AF 53.4%), and an enriched NCOR2 mutation (A4942C, case ERLR_08, primary AF 4.4%, recurrence AF 19.4%). The gene discussed is ARID1A; the disease is atrial fibrillation.