Notably, Tang et al. [32] have recently found that CTNND1(delta-catenin) was highly expressed in HCC tissues and dramatically enhanced Wnt/β-catenin signaling, indicating CTNND1 might act as a regulator of the canonical Wnt/β-catenin signaling pathway [33]. This evidence concerns the gene CTNND2 and hepatocellular carcinoma.