PTBP1 and hepatocellular carcinoma: The disruption of the MRG15-PTB interaction alters the location of the SF PTB and decreases the recruitment of the SF PTB to exon IIIb, promoting exon IIIb inclusion in the course of FGFR2 (fibroblast growth factor receptor 2) splicing [101] and consequently producing the FGFR2-IIIb isoform, which decreases the proliferation and migratory potential of HCC [102] (Fig. 5c).