Kaplan-Meier analysis of another dataset involving 293 lung tumor samples (GEO dataset GSE30219) revealed that high expression levels of CASC15 significantly correlated with a reduction in overall survival in NSCLC patients (log-rank test, p = 0.00054, Fig. 1b), suggesting that CASC15 upregulation might be crucial in NSCLC tumorigenesis and progression. The gene discussed is CASC15; the disease is non-small cell lung carcinoma.