TP53 and chronic myelogenous leukemia, BCR-ABL1 positive: The PQDS-specific serum miRNAs were specially implicated in several additional pathways such as ECM-receptor interaction, fatty acid metabolism, FoxO signaling, chronic myeloid leukemia, cell cycle, p53 signaling, central carbon metabolism in cancer, colorectal cancer and transcriptional misregulation in cancer (Fig. 3c right).