Lower PSD95 and synapsin I were found in the hippocampus of the PTSD group compared with the control group, but there was no significant difference between the Sh-miR and the control group (PSD95: F(3, 20) = 6.834, P = 0.0024, Fig. 2d; synapsin I: F(3, 20) = 7.915, P = 0.0011, Fig. 2e). The gene discussed is SYN1; the disease is post-traumatic stress disorder.